げっ歯類前帯状回皮質における負の報酬情報にもとづいた柔軟な行動調整の神経回路機構 / Prefrontal cortical mechanisms of flexible behavioral adjustments based on negative reward information in the rodent

Neuroscience Seminar (in English) (Dr. Daigo Takeuchi, University of Tokyo), "Prefrontal cortical mechanisms of flexible behavioral adjustments based on negative reward information in the rodent"

開催日

  • 2023/7/7

    16:00~17:00

開催場所(方法)

Seminar room(small), Science Frontier Laboratory (医学研究科 先端科学研究棟1F セミナー室)

詳細

Abstract
An essential component of learning and decision-making is the ability to learn reward structures of the environment which an animal interacts with and to make model-based inferences for swiftly adapting its choice behaviors in response to changes in the rules of the environment. Prefrontal cortical circuits are thought to play critical roles in such behavioral flexibility. However, it remains unclear how the prefrontal cortex implements model-based inference and adjust the animal’s choice actions in particular behavioral contexts. In this seminar, I present an experimental evidence regarding how anterior cingulate cortex (ACC) in rats play a role in reward-based sequential decision making. I will then discuss how the reinforcement learning framework may help further dissecting the decision algorithms that these prefrontal cortical circuits implement.

References
“Cingulate-motor circuits update rule representations for sequential choice decisions.” Nat. Commun. 13, 4545 (2022); Daigo Takeuchi, Dheeraj Roy, Shruti Muralidhar, Takashi Kawai, Chanel Lovett, Heather A. Sullivan, Ian R. Wickersham, Susu

申し込み

不要

お問い合わせ

小川正晃, ogawa.masaaki.7m@kyoto-u.ac.jp

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