M.D., Ph.D. Professor Koji Kawakami
We perform clinical epidemiology and pharmacoepidemiology studies in all clinical areas utilizing various large scale Japanese-based medical or health checkup databases. We conduct clinical research by turning various questions in medical practice (clinical questions) into researchable designs (research questions). The purpose of research projects is to identify the outcomes and safety of drug, surgery, medical device, and therapeutic regimen.
Research and Education
Under the mentorship of our faculty members who are well versed in clinical epidemiology and biostatistics, graduate students conduct clinical research to solve clinical questions using various real-world medical data, and epidemiological research for preventive medicine using pregnancy, infant, and school health checkup data provided by the local municipalities.
We build and utilize the databases (DB): electronic medical record DB (234 medical institutions, 26 million patients), maternal, infant, and school health checkup data (124 municipalities, 450,000 people). And we also utilize the databases: medical claims receipt DB (16 million patients), Diagnosis Procedure Combination (DPC) (35 million patients), and so on.
Our lab members, graduate students and faculty members, include professionals from a broad range of medical and health-related fields, including various specialties of medicine, nursing, and pharmacy. They are composed of MD (70%), pharmacists (20%), and statisticians and other professionals (10%). Our laboratory has produced 9 professors, 2 associate professors, and many leaders including a director of large hospitals and of national centers.
Pharmacoepidemiology laboratory orientation (April 2024)
(Left figure) Local municipalities participated in the school health check-up analyses program
(Right figure) Medical institutions participated in the electronic medical record analyses program
Recent Publications
(As of April 2024)
- Inayama Y, Mizuno K, Egawa M, Yamaguchi K, Hamanishi J, Takeuchi M, Mandai M, Kawakami K. Real-world practice of estrogen and progestogen prescriptions in menopausal women in Japan: A descriptive study using a Japanese claims database. Journal of Obstetrics and Gynaecology Research, DOI: 10.1111/jog.15795, 2023.
- Kuwauchi A, Yoshida S, Takeda C, Yamashita Y, Kimura T, Takeuchi M, Kawakami K. Validity of using Japanese administrative data to identify inpatients with acute pulmonary embolism: Referencing the COMMAND VTE registry. Journal of Epidemiology, doi.org/10.2188/jea.JE20220360, 2023.
- Masuda S, Fukasawa T, Takeuchi M, Arai K, Fujibayashi S, Otsuki B, Murata K, Shimizu T, Matsuda S, Kawakami K. Are dental procedures associated with pyogenic vertebral osteomyelitis? Clinical Orthopaedics and Related Research, in press, 2023.
- Yanai T, Yoshida S, Takeuchi M, Kawakami K. Pneumonia hospitalization after introduction of pneumococcal conjugate vaccine in Japan: Descriptive study using a nationwide claims database. Vaccine, in press, 2023.
- Takeuchi M, Shinkawa K, Yanagita M, Kawakami K. Hypothetical intervention of targeted systolic blood pressure control of <120 mm Hg on renal prognosis for persons with stage 3–4 chronic kidney disease: An application of parametric g-formula using health checkup data in Japan. Clinical and Experimental Nephrology, DOI: 10.1007/s10157-023-02341-1, 2023.
Laboratory
Koji Kawakami, MD, PhD, Professor and Chair
Yoko M. Nakao, MD, PhD, Associate Professor
Megumi Yuno, MPP, PhD, Associate Professor
Kayoko Mizuno, MD, PhD, Assistant Professor
Atsushi Takayama, MD, MPH, PhD, Assistant Professor
Toshiki Fukasawa, MS, Assistant Professor
Takanori Yanai, MD, Assistant Professor
Shiho Koizumi, MPH, Assistant Professor
General contact: （Email）info@pe.sph.med.kyoto-u.ac.jp
URL:https://kupe.med.kyoto-u.ac.jp/