M.D., Ph.D. Professor Shuichi Matsuda
Orthopaedic Surgery
We are orthopedic surgeons who treat patients suffering from diseases and injuries of the musculoskeletal system. Most people experience knee, shoulder, or lower back pain at some point in their lives. Femoral or vertebral fractures are the second most common cause of elderly individuals becoming bedridden.
We believe that overcoming functional disabilities of the musculoskeletal system contributes not only to the well-being of individual patients but also to the welfare of society as a whole. Our goal is to enable everyone to move their bodies freely and without difficulty throughout their lives.
Research and Education
The Biomaterials Group has developed many orthopedic implants—especially bioactive ones—some of which have already been applied in clinical settings. The team is actively developing bioactive and antibacterial metal implants. The Biomechanics Group is working on the development of a new knee prosthesis using computer simulation technology and is also analyzing spinal biomechanics. The Tumor Group is researching the molecular mechanisms involved in the development of bone and soft tissue tumors, with the aim of applying these findings to clinical practice. Regenerative therapy for damaged musculoskeletal tissues is being advanced through collaboration with the Center for iPS Cell Research and Application (CiRA). A clinical trial for cartilage regeneration therapy using iPS cell technology to treat knee cartilage injuries is currently in preparation. The Cartilage Metabolism and Rheumatology Group is experimentally investigating the mechanisms of joint destruction in osteoarthritis and rheumatoid arthritis. The group is also developing novel therapies in collaboration with other departments and research institutes. The Peripheral Nerve Group is focused on nerve regeneration, including the clinical application of nerve conduits created from autologous cells using 3D printing technology.
Computer simulation for total knee arthroplasty
Recent Publications
- Measurement of the Acetabular Cup Orientation After Total Hip Arthroplasty Based on 3-Dimensional Reconstruction From a Single X-Ray Image Using Generative Adversarial Networks. Fujita A, Goto K, Ueda A, Kuroda Y, Kawai T, Okuzu Y, Okuno Y, Matsuda S. J Arthroplasty. 2025 Jan;40(1):136-143.e1. doi: 10.1016/j.arth.2024.06.059. Epub 2024 Jun 27.PMID: 38944061
- Correlation Between Quantitative Cage Pressure Measurements and Surgeons' Qualitative Tactile Assessments During Extraction in Lumbar Lateral Interbody Fusion: A Cadaveric Study. Sono T, Shimizu T, Murata K, Yamamoto K, Matsuda S, Otsuki B. Spine (Phila Pa 1976). 2024 Oct 11. PMID: 39394653
- Number of Levels of Spinal Fusion Associated with the Rate of Joint-Space Narrowing in the Hip. Kawai T, Shimizu T, Goto K, Kuroda Y, Okuzu Y, Fujibayashi S, Matsuda S.J Bone Joint Surg Am. 2021 Jun 2;103(11):953-960.
- Medial Laxity Leads to Inferior Postoperative Clinical Outcomes and Function in Total Knee Arthroplasty. Nakamura S, Kuriyama S, Nishitani K, Morita Y, Morita Y, Matsuda S. J Arthroplasty. 2025 Feb 27:S0883-5403(25)00191-3. doi: 10.1016/j.arth.2025.02.063. Online ahead of print.PMID: 40023462
- Nerve regeneration using a Bio 3D conduit derived from umbilical cord-Derived mesenchymal stem cells in a rat sciatic nerve defect model. Iwai T, Ikeguchi R, Aoyama T, Noguchi T, Yoshimoto K, Sakamoto D, Fujita K, Miyazaki Y, Akieda S, Nagamura-Inoue T, Nagamura F, Nakayama K, Matsuda S. PLoS One. 2024 Dec 23;19(12):e0310711. doi: 10.1371/journal.pone.0310711. eCollection 2024.PMID: 39715170
Laboratory
Professor ： Shuichi Matsuda
Associate Professor ： Bungo Otsuki
Senior Lecturer ： Shinichi Kuriyama, Kohei Nishitani
Assistant Professor ： Toshiyuki Kawai, Takashi Noguchi, Yaichiro Okuzu
Program-Specific Assistant Professor, University Hospital ：Takayoshi Shimizu, Takashi Sono, Yoshiharu Shimozono, Sadaki
Mitsuzawa
[Department of Musculoskeletal Reconstruction(Endowed Chair)]
Program-Specific Associate Professor : Akio Sakamoto
Program-Specific Senior Lecturer : Shinichiro Nakamura,
Program-Specific Assistant Professor ： Yugo Morita
[Department of Advanced Medicine for Rheumatic Diseases (Endowed Chair)]
Program-Specific Senior Lecturer ： Koichi Murata
[Center for Rheumatic Diseases]
Program-Specific Assistant Professor, University Hospital ：Takayuki Fujii
[Rehabilitation Medicine]
Professor ： Ryosuke Ikeguchi