M.D., Ph.D. Professor Ryosuke Ikeguchi
Rehabilitation enables patients with physical disabilities to lead meaningful lives once again, both physically and mentally. While modern medicine is highly specialized in treating specific organs with a high level of expertise, rehabilitation medicine takes a holistic approach. It uses medical tools to diagnose and evaluate dysfunctions in the nervous, muscular, and skeletal systems caused by various diseases, providing treatment to help patients achieve a better quality of life.
Research and Education
As mentioned above, the Department of Rehabilitation Medicine treats a wide variety of diseases and is one of the hospital’s busiest departments in terms of patient volume. We verify and report the effectiveness of rehabilitation for many conditions using extensive data. For cerebrovascular disease, we have demonstrated the usefulness of walking training with the robot suit HAL after acute brain injury. In the context of musculoskeletal diseases, we have reported on the evaluation of skeletal muscle computed tomography**1** images in relation to physical function following total hip arthroplasty. In cancer rehabilitation, we have identified prognostic factors for patients with bone metastases based on their activities of daily living at the time of hospitalization. For respiratory diseases, we have reported on the safety and effectiveness of early mobilization for COVID-19 patients requiring ventilators. In basic science, we have investigated peripheral nerve regeneration using a Bio 3D printer and conducted an investigator-initiated clinical trial**2**.

Bio 3D nerve conduit manufacturing and transplantation
Recent Publications
- Kitamura G, Nankaku M, Kikuchi T, Nishi H, Tanaka H, Nishikawa T, Yonezawa H, Kajimoto T, Kawano T, Ohtagaki A, Mashimoto E, Miyamoto S, Ikeguchi R, Matsuda S. Effect of gait distance during robot training on walking independence after acute brain injury. Assist Technol. 2023 Feb 28:1-6.
- Kawano T, Nankaku M, Murao M, Hamada R, Goto K, Kuroda Y, Kawai T, Ikeguchi R, Matsuda S. Recovery of Muscle Atrophy and Fatty Infiltration in Patients with Acetabular Dysplasia After Total Hip Arthroplasty. J Am Acad Orthop Surg. 2022 Feb 1;30(3):e317-e326.
- Hamada R, Sato S, Miyasaka J, Murao M, Matsushita M, Kajimoto T, Otagaki A, Asano T, Nankaku M, Kondo T, Arai Y, Kanda J, Takaori-Kondo A, Ikeguchi R, Matsuda S. Belt Electrode-Skeletal Muscle Electrical Stimulation During Early Hematopoietic Post-Transplantation To Prevent Skeletal Muscle Atrophy and Weakness. Transplant Cell Ther. 2023 Jan;29(1):51.e1-51.e7.
- Nankaku M, Ikeguchi R, Aoyama T, Kitamura G, Otagaki A, Hamada R, Yuri T, Matsuda S. A First View of the Effect of a Trial of Early Mobilization on the Muscle Strength and Activities of Daily Living in Mechanically Ventilated Patients With COVID-19. Arch Rehabil Res Clin Transl. 2022 Sep;4(3):100201.
- Ikeguchi R, Aoyama T, Noguchi T, Ushimaru M, Amino Y, Nakakura A, Matsuyama N, Yoshida S, Nagai-Tanima M, Matsui K, Arai Y, Torii Y, Miyazaki Y, Akieda S, Matsuda S. Peripheral nerve regeneration following scaffold-free conduit transplant of autologous dermal fibroblasts: a non-randomised safety and feasibility trial. Commun Med (Lond). 2024 Jan 26;4(1):12.
Laboratory
[Professor]; Ryosuke Ikeguchi
[Assistant Professor]; Naoya Tanabe
[Graduate School of Medicine Human Health Science] Professor; Tomoki Aoyama