M.D., Ph.D. Professor Naoki Morimoto
Department of Plastic and reconstructive surgery, Kyoto University, was founded in 1977. Plastic and reconstructive surgery is a specialized branch of surgery to repair deformities and defects of the integument and underlying musculocutaneous framework. We not only conduct clinical studies for improvement of diagnostic skills and surgical outcomes but also focus on basic research into wound healing, microcirculation, embryology, anatomy, biomaterials and regenerative medicine. One of our achievements in skin regeneration has already been used clinically. We will constantly perform clinically useful research by applying the outcomes of basic research.
Research and Education
Current research activities in our field deal with clinical studies and basic studies such as regenerative medicine and wound healing. Clinical and basic studies are closely linked. In regenerative medicine, we developed the artificial dermis in cooperation with the Institute for Frontier Medical Science and it has been clinically used in the world. We have been conducting researches with a view to developing an ideal artificial skin. Recently we have performed clinical trials on a new artificial dermis which can provide sustained release of cell growth factors that was approved as a new medical device in 2018. We have also been engaged in studies on regeneration of the adipose tissue. In wound healing, we are putting a great deal of effort into elucidating pathogenesis of keloid using molecular biological technique and developing its new treatment.
We are training young researchers to have both scientific and clinical perspectives and to aim at performing creative studies which are put to clinical application.
left：3-dimensional craniofacial developmentduring the early prenatal period（ref.1）、center：Photoacoustic tomographic projection images of ALT flap（ref.2）、right：Melanocytic nevus after inactivation by high hydrostatic pressure（ref.5）
Staff members in Plastic and Reconstructive Surgery
Recent Publications
- Yamanaka H, Sawaragi E, Nakano T, Katayama Y, Ito T, Tada H, Hidaka Y, Morita S, Funakoshi C, Kinoshita A, Watanabe M, Tsuge I, Katsube M, Sakamoto M, Yamaoka T, Morimoto N. A high-hydrostatic pressure device for nevus tissue inactivation and dermal regeneration for reconstructing skin defects after giant congenital melanocytic nevus excision: a clinical trial. Regenerative Therapy, 2023; 24: 167-173.
- Sakamoto M, Minaki Y, Nakano T, Tsuge I, Yamanaka H, Sowa Y, Shimizu Y, Inoie M, Saito S, Morimoto N. A novel approach for wound treatment using dried cultured epidermal allograft: A Phase I/II, Single-centre, Open-label clinical trial. Burns, 2023; 49(5): 1079-1086.
- Katsube M, Utsunomiya N, Katayama Y, Yamanaka H, Tsuge I, Sowa Y, Sakamoto M, Morimoto N. Interposition grafting of collagen-gelatin sponge impregnated with basic fibroblast growth factor in primary palatoplasty. Regenerative Therapy, 2023; 24: 288-293.
- Tsuge I, Munisso MC, Kosaka T, Takaya A, Sowa Y, Liu C, Yamamoto G, Saito S, Morimoto N. Preoperative visualization of midline-crossing subcutaneous arteries in transverse abdominal flaps using photoacoustic tomography. Journal of Plastic, Reconstructive & Aesthetic Surgery, 2023; 84: 165-175.
- A Makino, S Saito. Morphological changes in postaxial polydactyly of the foot: A standardized quantitative analysis using the watanabe–fujita classification. Plastic and Reconstructive Surgery, 2024; 153(1): 170e-180e.
研究室
Professor：Naoki Morimoto M.D.,Ph.D.
Specially Appointed Professor：Yasuhiko Tabata Ph.D.
Associate Professor：Susumu Saito M.D.,Ph.D.
Lecturer：Itaru Tsuge M.D.,Ph.D.
Assistant Professor：Motoki Katsube M.D.,Ph.D.
Assistant Professor：Hiroki Yamanaka M.D.,Ph.D.
Assistant Professor：Natsuko Utsunomiya M.D.,Ph.D.
Specific hospital Assistant Professor：Yasuhiro Katayama M.D.,Ph.D.
Specific hospital Assistant Professor：Eiichi Sawaragi M.D.
TEL: +81-75-751-3613
FAX: +81-75-751-4340
e-mail: prs_info@kuhp.kyoto-u.ac.jp
URL: http://keisei.kuhp.kyoto-u.ac.jp/