Orthopaedic Surgery, Division of Reconstruction for Musculoskeletal Disorders

shfuji Shunsuke Fujibayashi, MD, PhD. Program-Specific Professor

The purpose of our research program is the reconstruction of musculoskeletal disorders in orthopaedic surgery. The loss of locomotor function reduces the patient’s quality of life. if it takes time to reconstruct the function, there is a risk of disuse syndrome and complications of other organ diseases. Rapid functional reconstruction using artificial joint, metal implant, and artificial bone is desired for such patients. We are developing patient-specific and disease-specific medical device for next-generation surgery.

Research and Education

Artificial joint: We are developing original artificial hip joint implant, which have superior mechanical properties and biocompatibility. Currently we are developing bioactive bone cements for arthroplasties, as well as bioabsorbable screws for the reconstructive surgeries. The artificial knee joint aims to improve long-term durability and patient satisfaction by analyzing the knee joint kinematics using computer simulations.
Spinal fusion cage: We have developed a spinal fusion cage using bioactive porous titanium porous and are applying it clinically.
Biomaterials: We are developing artificial bones that have a high affinity with living bone. By applying special treatment to the surface of titanium metal and polymer, we are developing new artificial bones and artificial joints that have functions such as bone formation and antibacterial properties. And additive manufacturing technology is introduced to realize the patient-specific and disease-specific devices.

Figure1: Computer simulation of artificial knee joint
Figure2: Spinal fusion using our developed bioactive porous titanium cage



Recent Publications

  1. Fujibayashi S, Takemoto M, Nakamura T, Matsushita T, Kokubo T, Sasaki K, Mori S, Matsuda S. Stand-Alone Anterior Cervical Discectomy and Fusion Using an Additive Manufactured Individualized Bioactive Porous Titanium Implant without Bone Graft: Results of a Prospective Clinical Trial. Asian Spine J 2021;15(3):1-8
  2. Masamoto K,Fujibayashi S, Yamaguchi S, Otsuki B, Okuzu Y, Kawata T, Goto K, Shimizu T, Shimizu Y, Kawai T, Hayashi M, Morizane K, Imamura M, Ikeda N, Takaoka Y, Matsuda S. Bioactivity and antibacterial activity of strontium and silver ion releasing titanium. J Biomed Mater Res B Appl Biomater. 2020 Aug 6. doi: 10.1002/jbm.b.34695. Online ahead of print.PMID: 32767436
  3. Shimizu Y,Fujibayashi S, Yamaguchi S, Mori S, Kitagaki H, Shimizu T, Okuzu Y, Masamoto K, Goto K, Otsuki B, Kawai T, Morizane K, Kawata T, Matsuda S. Bioactive effects of strontium loading on micro/nano surface Ti6Al4V components fabricated by selective laser melting. Mater Sci Eng C Mater Biol Appl. 2020 Apr;109:110519. doi: 10.1016/j.msec.2019.110519. Epub 2019 Dec 5.
  4. Nishitani K, Kuriyama S, Nakamura S, Umatani N, Ito H, Matsuda S. Excessive flexed position of the femoral component was associated with poor new Knee Society Score after total knee arthroplasty with the Bi-Surface knee prosthesis. Bone Joint J. 2020 Jun;102-B(6_Supple_A):36-42. doi: 10.1302/0301-620X.102B6.BJJ-2019-1531.R1. PMID: 32475263
  5. Nakamura S, Shima K, Kuriyama S, Nishitani K, Ito H, Matsuda S. Tibial Tubercle-Trochlear Groove Distance Influences Patellar Tilt After Total Knee Arthroplasty. The Journal of Arthroplasty 34 (2019) 3080-3087

Orthopaedic Surgery, Division of Reconstruction for Musculoskeletal Disorders

Program-Specific Professor:Shunsuke Fujibayashi
Program-Specific Assistant Professor:Shinichiro Nakamura・Kohei Nishitani