Organogenetic Induction

kaoYoshiya Kawaguchi, MD, Ph.D. Professor  btn

Research and Education



Recent Publications

1.Furuyama K, Kawaguchi Y*, Akiyama H*, Horiguchi M, Kodama S, Kuhara T, Hosokawa S, Elbahrawy A, Soeda T, Koizumi M, Masui T, Kawaguchi M, Takaori K, Doi R, Nishi E, Kakinoki R, Deng JM, Behringer RR, Nakamura T, Uemoto S
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine.
Nat Genet. 43: 34-41, 2011
2. Kawaguchi Y*, Takaori K, Uemoto S
Genetic lineage tracing, a powerful tool to investigate the embryonic organogenesis and adult organ maintenance of the pancreas.
J Hepatobiliary Pancreat Sci. 18: 1-5, 2011
3. Fukuda A, Kawaguchi Y*, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Kawaguchi M, Terao M, Doi R, Wright CV, Hoshino M, Chiba T, Uemoto S
Reduction of Ptf1a gene dosage causes pancreatic hypoplasia and diabetes in mice.
Diabetes. 57: 2421-2431, 2008
4.  Fukuda A, Kawaguchi Y*, Furuyama K, Kodama S, Kuhara T, Horiguchi M, Koizumi M, Fujimoto K, Doi R, Wright CVE, Chiba T
Loss of the major duodenal papilla results in brown pigment biliary stone formation in pdx1 null mice.
Gastroenterology. 130: 855-67. 2006
5. Fukuda A, Kawaguchi Y*, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Koizumi M, Boyer DF., Fujimoto K, Doi R, Kageyama R, Wright CVE, Chiba T
Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.
J Clin Invest. 116: 1484-93. 2006


Professor Yoshiya Kawaguchi
TEL +81-75-366-7049
FAX +81-75-366-7050;