kao Toshiya Murai Professor , M.D., btn

The Department of Psychiatry was established in September 1902. From then onward, our Department has continued to play an important role as a clinical research center for psychiatry in Japan, in particular, in the fields of psychopathology, neuropsychology, neuropathology, epileptology, child and forensic psychiatry. We will uphold this tradition as well as applying newly emerging techniques such as neuroimaging, we aim to be a clinical, research, and educational center of psychiatry with the best quality.

Research and Education

By applying neurobiological as well as psychosocial approaches flexibly, we aim to achieve a multi-faceted understanding of psychiatric disorders. Using high-resolutional MRI, the Neuroimaging Group is attempting to elucidate the neural correlates of various neuropsychiatric conditions including schizophrenia, depression, and behavioral addictions. The Psychopathology Group focuses on symptomatology as well as psychotherapy in various psychiatric conditions including eating disorders. In collaboration with brain surgeons and occupational and speech therapists, the Neuropsychology Group is investigating neural correlates of cognitive and behavioral sequelae after brain damage. The Child and Adolescent Psychiatry Group is currently focusing on relationships between phenotypes and neurocognitive functions, as well as effectiveness of various interventions. Collaborations among these groups are very active, and, as a result, our Department remains to be a best clinical, research, and educational center of psychiatry.

r-060-11.Visualization of thalamo-frontal fibers and frontal cortices (JAMA Psychiatry, 2013).

r-060-22.The psychiatric department building.

Recent Publications

  1. Kubota M, Miyata J, Sasamoto A, Yoshida H, Kawada R, Fujimoto S, Tanaka Y, Sawamoto N, Fukuyama H, Takahashi H, Murai T. Thalamocortical disconnection within the orbitofrontal region associated with cortical thinning in schizophrenia. JAMA Psychiatry70:12-21, 2013.
  2. Isobe M, Tanigaki K, Murak K, Miyata J, Takemura A, Sugihara G, Takahashi H, Aso T, Fukuyama H, Hazama M, Murai T. Polymorphism within a neuronal activity-dependent enhancer of NgR1 is associated with corpus callosum morphology in humans. Molecular Neuropsychiatry 1: 105-115, 2015.
  3. Sugihara G, Oishi N, Son S, Kubota M, Takahashi H, Murai T. Distinct patterns of cerebral cortical thinning in schizophrenia: a neuroimaging data-driven approach. Schizophrenia Bulletin 43: 900-906, 2017.
  4. Ueno T, Oishi N, Murai T. Sex-specific regional gray matter volume correlates of daily activities. Scientific Reports, 8: 9935, 2018.
  5. Aso T, Sugihara G, Murai T, Ubukata S, Urayama SI, Ueno T, Fujimoto G, Thuy DHD, Fukuyama H, Ueda K. A venous mechanism of ventriculomegaly shared between traumatic brain injury and normal ageing. Brain 143:1843-1856, 2020.


Professor: Toshiya Murai
Senior Lecturer: Jun Miyata, Hironobu Fujiwara
Assistant Professor: Taro Suwa, Masaaki Hazama, Naoko Sugita, Yujiro Yoshihara, Masanori Isobe, Teruhisa Uwatoko, Manabu Kubota, Hirotsugu Kawashima, Haruka Kozuki, Kosuke Tsurumi
Program-Specific Assistant Professor: Sadao Otsuka
TEL: +81-75-751-3386
FAX: +81-75-751-3246