Integrative Brain Science


Progress in various methods of research has opened the doors to revealing much about the integrative functions of the brain, such as emotion, consciousness, and the mind. The brain is an organ for information processing acquired in the course of evolution, and it is a highly sophisticated system made up of over 100 billion intertwined neurons. The study of the brain is not complete unless approached from both the biological and the computational aspects. People proficient in all sorts of disciplines are invited to collaborate in exploring this ultimate theme.

Research and Education

Various techniques employed in neuroscience, such as molecular biology, neuroanatomy, neurophysiology, and imaging techniques are constantly unfolding and reporting new findings. In our laboratory, we address the brain as an information processing system, and apply molecular biology, neurophysiology, psychophysics and computational techniques to study the function of the intricate neural network that is behind human perception, action and thought. We focus, in particular, on cognitive functions, sensorimotor functions and regenerations of functions. To fully understand the brain functions, we have found that simultaneously application of two approaches most effective. One is the analytical approach based on the biological properties of the neurons and their connections, and the other is an integrative high level systems approach by computational neuroscience. We will continue to pursue this theme in studying higher brain functions. Education and training of young prospective researchers are also our primary concern. We have a comprehensive series of lectures and seminars for graduate school students.
1. Successful axon regeneration across the debrided lesion in adult rat spinal cord 2. Cortical areas related to smooth eye movements

Recent Publications

  1. Nishio T, Fujiwara H, Kanno I. Immediate elimination of injured white matter tissue achieves a rapid axonal growth across the severed spinal cord in adult rats. Neurosci Res. 131:19-29, 2018
  2. Nohara S, Kawano K, *Miura K. Difference in perceptual and oculomotor responses revealed by apparent motion stimuli presented with an inter-stimulus interval. J Neurophysiol, 113(9):3219-28, 2015.
  3. Miura K, Inaba N, Aoki Y, Kawano K. Difference in visual motion representation between cortical areas MT and MST during ocular following responses. J Neurosci. 34(6):2160-8, 2014.
  4. Sugita Y, Miura K, Araki F, Furukawa T, Kawano K. Contributions of retinal direction-selective ganglion cells to optokinetic responses in mice. Eur J Neurosci. 38(6):2823-31, 2013.
  5. Nishio T, Kawaguchi S, Fujiwara H. Emergence of highly neurofilament-immunoreactive zipper-like axon segments at the transection site in scalpel-cordotomized adult rats. Neuroscience. 155(1):90-103, 2008

Integrative Brain Science

Assistant Professor : Takeshi Nishio
Assistant Professor : Kenichiro Miura
TEL : +81-75-753-4481
FAX : +81-75-753-4486
e-mail : kmiura [at]