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Institute of Laboratory Animals Congenital Anomaly Research Center
Center for Anatomical Studies Human Brain Research Center
Center for Genomic Medicine Center for Medical Education
Kyoto University Medical Science and Business Liaison Office Support Center

Institute of Laboratory Animals
Institute of Laboratory Animals The Institute of Laboratory Animals (ILA) was established in May 1972 as a joint research facility for animal experiments carried out in the School of Medicine (now the Graduate School of Medicine and Faculty of Medicine). As well as conducting animal experiments for the purposes of medical science, ILA manages breeding programs to produce laboratory animals. Furthermore, the Institute is engaged in the development of laboratory animals, and conducts education programs and research in this area.

The building currently occupied by the ILA is an extended and improved version of the original premises, and has been used in its present form since July 2003. Equipped with the most up-to-date facilities and functions, the building was designed and constructed in accordance with the following priorities:
1. Spacious (adequate space for breeding experiments)
2. Aesthetically pleasing (attractive, hygienic, and highest safety standards; free of offensive odors, out of consideration both for personnel working in the building and the environment)
3. User-friendly (emphasis on functionality, security measures, and low running costs)

It is hoped that the ILA will be widely utilized and that the research results obtained through animal experiments will contribute to advancements in biomedical science as well as to the development and improvement of methods of disease prevention and treatment.

The ILA has also been the core facility for the National BioResource Project for the Rat in Japan since fiscal 2002.


Congenital Anomaly Research Center

The Congenital Anomaly Research Center was established in April 1975 for the purpose of conducting research into human prenatal medicine and the prevention of congenital anomalies (birth defects). Since 1961, 44,000 specimens of human embryos and fetuses have been collected and preserved, and records maintained. Of these, around 1,000 undamaged embryos that are up to the 8th week following fertilization, which corresponds to the organogenesis stage, have been preserved as whole-body serial specimens.

An 8-week human embryo in the amniotic sac

With 474 particularly high quality examples of such embryos being included in international human embryo registers, the Center ranks second only to the Carnegie Collection in the U.S., which has 617 specimens of similar quality. The Congenital Anomaly Research Center has the largest and highest quality collection of human embryos in the world, and is available for use by researchers in related fields both in Japan and overseas.

The Center is currently conducting research into the early stages of abnormal morphogenesis, using genetic epidemiology methods to elucidate the etiology of various types of birth defects. In addition, experimental research is being conducted on the genesis mechanism for birth defects in order to identify some preventive measures. The Center is one of the leading centers of human embryology and congenital anomaly research in the world.

From September 2005 to August 2008, the Center will implement the Project for Establishing a Database of 3D Human Embryo Images, selected as part of the Japan Science and Technology Agency bioinformatics promotion scheme. Using the specimens preserved at the Center, this project will create a database of MR images of fetuses in each stage of development, from the organogenesis stage until birth. In addition, the project will take MR tomographic images and serial section images to produce three-dimensional images of the formation of fetuses in each stage of development as well as of the main organs, and create a database of these images.


Center for Anatomical Studies

Center for Anatomical Studies The Center for Anatomical Studies was set up in 1982 to provide a modern and integrated facility for a range of activities concerned with human body dissection. The creation of the Center meant that lectures on morphology, practical training, routine dissection work, and research, which had previously been conducted in the anatomy, pathology, and legal medicine buildings, could now be performed in a single location. The Center is the leading establishment of its kind in the country, comprising modern dissecting rooms, dissection practice facilities, specimen depository, medical data room, laboratories, and specimen preparation rooms. A lecture hall, histology practical training room, and audiovisual study room are located in the west wing. In 1998, the audiovisual study room on the fourth floorof the west wing was renovated, and a Faculty of Medicine satellite seminar room was constructed as an annex to theAcademicCenter for Computing and Media Studies, KyotoUniversity. Since 2003, the Center has been providing support to researchers and graduate students in the Graduate School of Medicine for morphology research activities such as immunostaining.

The several thousand macroscopic specimens collected by the Center during the course of more than a century are on a scale unparalleled in the world. This, combined with its modern facilities and equipment, make the Center unique among universities.


Human Brain Research Center

Whole-head magnetoencephalography (306 sensors) and 3 tesla MRI scanner The Human Brain Research Center (HBRC) was established in April 2000 to further develop the world-class research into brain science being carried out in Kyoto University in a comprehensive way. Specifically, this meant integrating psychological, neurophysiological, and brain function imaging research; creating a center for non-invasive research into higher brain function; improving the overall efficiency of research; and making it possible to actively promote the sharing of the research facility both by those affiliated to the university as well as researchers from the wider community.

Currently, the activities of the HBRC go beyond the confines of neurophysiology and brain function imaging to encompass research into the normal brain as well as various kinds of neurological disorder, incorporating non-invasive research techniques.

By carrying out research on human subjects to elucidate the functions of the human brain and investigate the pathophysiology of the various disorders that occur in the human brain, the HBRC aims to obtain data that will be valuable in curing disease.

Center for Genomic Medicine

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Center for Medical Education

member of Center for Medical EducationTopics concerning medical education have currently become important issues for our community.
The traditional style of medical education has mainly been carried out through the efforts of individual departments of a medical school. Nowadays, however, it is impossible to provide an appropriate medical education without coordination of the efforts of individual sections. Therefore, the Center for Medical Education has been established at Kyoto University to play a central role in the promotion of modern medical education.


Kyoto University Medical Science and Business Liaison Office

Opened in April 2002, the Office addresses the issue of how research achievements can be best returned for the benefit of society. This aim can be said to be one of the three major objectives of national universities; the first two being the education and the research itself. Excavating the seeds of innovation born within the medical field (centering around the Graduate School of Medicine) the office contributes to the development of improved healthcare by matching the university seeds with the market and industrial needs for collaborations.

The KUMBL Office consists of the Business Liaison Office of Kyoto University Faculty of Medicine and the Incubation Plaza. The objective of the Business Liaison Office of Kyoto University Faculty of Medicine is to promote further advances in the development of medical treatment and technology. It bridges the faculties in the medical field with industry through compiling university research and knowledge and emitting them to the outside. The office engages itself in many other technology transfer activities such as gathering information on ongoing research and projects, and assisting university researchers with patent applications, licensing and collaboration. Also providing support for contract negotiation and setting up of the start-up business, the Business Liaison Office of Kyoto University Faculty of Medicine functions as a one-stop shop for university-academia collaboration for the medical field.

The Incubation Plaza is a committee (Incubation Program Committee) consisting of Kyoto University, Mitsubishi UFJ Capital and Sumitomo Corporation that aims to put advances in medical research into practical applications within society. The plaza creates start-up business by selecting the researches, which holds promising business potential and investing the funding from Mitsubishi UFJ and Sumitomo Corporation into them. Through collaboration with the new start-up, it further promotes the establishment of future university spinouts and advances in further research.




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