Clinical Physiology and Ultrasound Labo

Yasutomo Fujii, MD, PhD Professor

・ Laboratory science aims to establish and realize concepts and methods for extracting and analyzing various information from molecular and cellular levels to the organ level, for the purpose of elucidating structure and function of livings, clarifying etiology and pathophysiology of various diseases and establishing diagnosis and treatment of diseases. In this area, we focus on structural and functional analysis indispensable for diagnosis or treatment of diseases. Accordingly, we promote studies on new concept and technology on the basis of medicine, biology and information technology. We intend to encourage new talents who will act as a leader in the fields of education, research and clinical practice.

Research and Education

・ Our laboratory has some projects related with not only ultrasound tissue characterization: development of a novel diagnostic imaging modality using some acoustic parameters but also therapeutic application of ultrasound energy. Evaluation of functional disorders of the organs using extracorporeal ultrasound, whose non-invasiveness can make it possible to do it under physiological conditions, is one of our projects. Some clinical researches on new fields, such as diagnosis of gastrointestinal diseases, will be launched in Ultrasound Center of Kyoto University Hospital. Moreover, also is our challenge construction of a new system for contributing community health care, for example, an application of portable ultrasound equipments for the care of in-home patients, in corporation with researchers in other fields, such as engineering, nursing and rehabilitation.

Power Doppler sonogram of hepatoceller carcinoma

Power Doppler sonogram of
hepatoceller carcinoma

Processed image of the Surface of 10 yen coin (left) using acoustic impedance difference imaging

Processed image of the Surface of 10 yen coin (left) using acoustic impedance difference imaging


1. Miyamoto, M., Kotani, K., Okada, K., Fujii, Y., Konno, K., Ishibashi, S., Taniguchi, N. The correlation of common carotid arterial diameter with atherosclerosis and diabetic retinopathy in patients with type 2 diabetes mellitus. Acta Diabetol 49; 63-68, 2012.
2. Fujii, Y., Yoshizawa, M., Emoto, R., Haruyama, N., Irie, T., Taniguchi, N.: Processed skin surface images acquired by acoustic impedance difference imaging using the ultrasonic interference method: a pilot study. J Med Ultrasonics 39; 37-42, 2012.
3. Koibuchi, H., Fujii, Y., Kotani, K., Konno, K., Mastsunaga H., Miyamoto M., Taniguchi, N.: Degradation of ultrasound probes caused by disinfection with alcohol. J Med Ultrasonics 38; 97-100, 2011.
4. Fujii, Y., Taniguchi, N., Itoh, K., Satoh M., Irie T.: Effect of repeated US stimulation on adiponectin secretion by adipocytes of obese human subjects. American Institute of Physics Conference Proceedings of 5th International Symposium on Therapeutic Ultrasound. 64-68, 2006.
5. Fujii, Y., Taniguchi, N., Akiyama, I., Tsao, JW., Itoh, K.: A new system for in vivo assessment of the degree of nonlinear generation using the second harmonic component in echo signals. Ultrasound in Medicine and Biology 30: 1511-1516, 2004.


Professor: Yasutomo Fujii

連絡先:Activity Database on Education and Research, Kyoto University