Particle Radiation Oncology, Radiation Oncology Research Laboratory

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Minoru Suzuki, M.D. Ph.D.Professor btn

Since 1990, boron neutron capture therapy (BNCT) greater than 450 have been carried out by our center in collaboration with outside researchers in medicine. Boron neutron capture therapy (BNCT) has a unique feature which can deliver tumor-cell selective heavy-particle irradiation (Fig.1). This feature makes BNCT possible to deal with patients suffering from malignant tumors that are refractory to conventional radiotherapy and particle radiotherapy(Fig.2). The mission of this division is to make BNCT a safe and effective treatment option for the patients suffering for refractory or recurrent tumors.

Research and Education

In 2008, accelerator-based BNCT system (AB-BNCT system) was constructed in Kyoto University Research Reactor Institute. Using this system, a clinical trial of BNCT for recurrent malignant brain tumors has been started since October in 2012. Development of an AB-BNCT system is an important first step for a future in which BNCT will be available in the hospital equipped with AB-BNCT system.

The main practical and research subjects are as follows;

1)Clinical trial using AB-BNCT system.

2)RB-BNCT for common cancer

3)Research on effect of BNCT for normal organs or tissues.

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Recent Publications

1.Suzuki M, et al. Boron neutron capture therapy outcomes for advanced or recurrent head and neck cancer.  J Radiat Res. (in press)

2.Suzuki M, et al. Reirradiation for locally recurrent lung cancer in the chest wall with boron neutron capture therapy (BNCT): A case report. Int Canc Conf J 2012;1:235–238

3.Suzuki M, et al. Impact of accelerator-based boron neutron capture therapy (AB-BNCT) on the treatment of multiple liver tumors and malignant pleural mesothelioma Radiather Oncol 2009;92: 89-95

4.Suzuki M, et al. A novel concept of treatment of diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT). Radiother Oncol. 2008;88:192-195

5.Suzuki M, et al. First attempt of boron neutron capture therapy (BNCT) for hepatocellular carcinoma  Jpn J Clin Oncol. 2007;37(5):376-81.

Particle Radiation Oncology

Radiation Oncology Research Laboratory

Particle Radiation Oncology

Professor:Minoru Suzuki, M.D. Ph.D.

URL: http://www.rri.kyoto-u.ac.jp/en/research_div/rls/prorc/pro

Assistant Professor:Natsuko Kondo, Masaru Narabayashi, Nozomi Fujimoto