We, orthopaedic surgeons, treat patients who suffer diseases and injuries in the musculo-skeletal system. Most of the people experience knee, shoulder, or low back pain in a lifetime. Femoral or vertebral fracture is the second popular cause that leads the elderly people to become bedridden. We believe that overcoming functional disability of the musculo-skeletal system contributes not only to the happiness of an individual patient but also to the welfare of our whole society. We aim for all people moving their body without difficulties throughout their life.
Research and Education
Skeletal formation/functional regulation group is focusing on genome-wide and systemic analyses of gene and protein expression, function in skeletogenesis using molecular biological, biochemical, and mouse genetics approaches. Biomaterial group has developed and is developing many bioactive implants, some of which have been applied clinically in orthopaedic surgery. Biomechanics group is developing a new knee prosthesis using computer simulation technology and analyzing spine biomechanics. Tumor group is researching on molecular mechanisms of generation of bone and soft tissue tumor and its application to clinical cases. Regenerative medicine in damaged skeleton is being advanced by collaboration with Center for iPS Cell Research and Application. Cartilage metabolism/rheumatology group is experimentally investigating the mechanisms of joint destruction in osteoarthritis and rheumatoid arthritis and developing novel therapies by collaboration with other departments and institutes. Peripheral nerve group is working on the nerve regeneration, trying to apply the method for treating nerve degeneration and injury.
Computer simulation for total knee arthroplasty
- Ikeguchi R, Kakinoki R, Ohta S, Oda H, Yurie H, Kaizawa Y, Mitsui H, Aoyama T, Toguchida J, Matsuda S. Recipient bone marrow-derived stromal cells prolong graft survival in a rat hind limb allotransplantation model. Microsurgery. 2017; 37(6):632-640.
- Kuriyama S, Ishikawa M, Nakamura S, Furu M, Ito H, Matsuda S. Noise Generation With Good Range of Motion but Without Femorotibial Instability Has Small Effect on Patient Satisfaction After Total Knee Arthroplasty. J Arthroplasty. 2017; 32(2):407-412.
- Murata K, Fang C, Terao C, Giannopoulou EG, Lee YJ, Lee MJ, Mun SH, Bae S, Qiao Y, Yuan R, Furu M, Ito H, Ohmura K, Matsuda S, Mimori T, Matsuda F, Park-Min KH, Ivashkiv LB. Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis. Immunity. 2017; 47(1):66-79 e5.
- Okuzu Y, Goto K, Kawata T, So K, Kuroda Y, Matsuda S. The Relationship Between Subluxation Percentage of the Femoroacetabular Joint and Acetabular Width in Asian Women with Developmental Dysplasia of the Hip. J Bone Joint Surg Am. 2017; 99(7):e31.
- Shimizu T, Fujibayashi S, Yamaguchi S, Otsuki B, Okuzu Y, Matsushita T, Kokubo T, Matsuda S. In vivo experimental study of anterior cervical fusion using bioactive polyetheretherketone in a canine model. PLoS One. 2017; 12(9):e0184495.
Orthopedic SurgeryProfessor ： Shuichi Matsuda
Associate Professor ： Hiromu Ito
Senior Lecturer ： Akio Sakamoto, Soichi Ohta
Assistant Professor ： Bungo Ohtsuki, Shinichi Kuriyama, Ryuzo Arai, Yutaka Kuroda, Toshiyuki Kawai
[Department of Musculoskeletal Reconstruction(Endowed Chair)]
Program-Specific Professor ： Shunsuke Fujibayashi
Program-Specific Senior Lecturer ： Koji Goto
Program-Specific Assistant Professor ： Shinichiro Nakamura
[Department of Advanced Medicine for Rheumatic Diseases (Endowed Chair)]
Program-Specific Assistant Professor ： Kohei Nishitani, Koichi Murata
[Institute for Advancement of Clinical and Translational Science(iACT)]
Associate Professor ： Takeshi Okamoto
Associate Professor ： Ryosuke Ikeguchi
URL ： http://www.kuhp.kyoto-u.ac.jp/~seikeigeka/