Toru Kita
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No. Publications Collaborations
1 2 3 4 5 6
1. Oikawa S, Kita T, Mabuchi H, Matsuzaki M, Matsuzawa Y, Nakaya N, Saito Y, Sasaki J, Shimamoto K, Itakura H; J-LIT Study Group.
Risk of coronary events in Japanese patients with both hypercholesterolemia and type 2 diabetes mellitus on low-dose simvastatin therapy: implication from Japan Lipid Intervention Trial (J-LIT).
Atherosclerosis, 191: 440-6, 2007.
           
2. Shibata Y, Kume N, Arai H, Hayashida K, Inui-Hayashida A, Minami M, Mukai E, Toyohara M, Harauma A, Murayama T, Kita T, Hara S, Kamei K, Yokode M.
Mulberry leaf aqueous fractions inhibit TNF-alpha-induced nuclear factor kappaB (NF-kappaB) activation and lectin-like oxidized LDL receptor-1 (LOX-1) expression in vascular endothelial cells.
Atherosclerosis, 193: 20-7, 2007.
           
3. Haruna Y, Kobori A, Makiyama T, Yoshida H, Akao M, Doi T, Tsuji K, Ono S, Nishio Y, Shimizu W, Inoue T, Murakami T, Tsuboi N, Yamanouchi H, Ushinohama H, Nakamura Y, Yoshinaga M, Horigome H, Aizawa Y, Kita T, Horie M.
Genotype-phenotype correlations of KCNJ2 mutations in Japanese patients with Andersen-Tawil syndrome.
Hum Mutat, 28: 208, 2007.
           
4. Tabuchi M, Inoue K, Usui-Kataoka H, Kobayashi K, Teramoto M, Takasugi K, Shikata K, Yamamura M, Ando K, Nishida K, Kasahara J, Kume N, Lopez LR, Mitsudo K, Nobuyoshi M, Yasuda T, Kita T, Makino H, Matsuura E.
The association of C-reactive protein with an oxidative metabolite of LDL and its implication in atherosclerosis.
J Lipid Res, 48: 768-81, 2007.
           
5. Tsuji K, Akao M, Ishii TM, Ohno S, Makiyama T, Takenaka K, Doi T, Haruna Y, Yoshida H, Nakashima T, Kita T, Horie M.
Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene.
J Mol Cell Cardiol, 42: 662-9, 2007.
           
6. Yoshida Y, Togi K, Matsumae H, Nakashima Y, Kojima Y, Yamamoto H, Ono K, Nakamura T, Kita T, Tanaka M.
CCN1 protects cardiac myocytes from oxidative stress via beta1 integrin-Akt pathway.
Biochem Biophys Res Commun, 355: 611-8, 2007.
           
7. Ohno S, Zankov DP, Yoshida H, Tsuji K, Makiyama T, Itoh H, Akao M, Hancox JC, Kita T, Horie M.
N- and C-terminal KCNE1 mutations cause distinct phenotypes of long QT syndrome.
Heart Rhythm, 4: 332-40, 2007.
           
8. Hosseinkhani M, Hasegawa K, Ono K, Kawamura T, Takaya T, Morimoto T, Wada H, Shimatsu A, Prat SG, Suemori H, Nakatsuji N, Kita T.
Trichostatin A induces myocardial differentiation of monkey ES cells.
Biochem Biophys Res Commun, 356: 386-91, 2007.
           
9. Hirai M, Ohbayashi T, Horiguchi M, Okawa K, Hagiwara A, Chien KR, Kita T, Nakamura T.
Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo.
J Cell Biol, 176: 1061-71, 2007.
           
10. Okabe TA, Shimada K, Hattori M, Murayama T, Yokode M, Kita T, Kishimoto C.
Swimming reduces the severity of atherosclerosis in apolipoprotein E deficient mice by antioxidant effects.
Cardiovasc Res, 4: 537-45, 2007.
           
11. Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Saito Y, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K; Japan EPA lipid intervention study (JELIS) Investigators.
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.
Lancet, 369: 1090-8, 2007.
           
12. Sumi E, Iehara N, Akiyama H, Matsubara T, Mima A, Kanamori H, Fukatsu A, Salant DJ, Kita T, Arai H, Doi T.
SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cells.
Am J Pathol, 170: 1854-64, 2007.
           
13. Tamura T, Furukawa Y, Taniguchi R, Sato Y, Ono K, Horiuchi H, Nakagawa Y, Kita T, Kimura T.
Serum adiponectin level as an independent predictor of mortality in patients with congestive heart failure.
Circ J, 71: 623-30, 2007.
           
14. Nishio Y, Sato Y, Taniguchi R, Shizuta S, Doi T, Morimoto T, Kimura T, Kita T.
Cardiac troponin T vs other biochemical markers in patients with congestive heart failure.
Circ J, 71: 631-5, 2007.
           
15. Shimamoto K, Kita T, Mabuchi H, Matsuzaki M, Matsuzawa Y, Nakaya N, Oikawa S, Saito Y, Sasaki J, Itakura H; J-LIT Study Group.
Effects of hypertension and type 2 diabetes mellitus on the risk of total cardiovascular events in Japanese patients with hypercholesterolemia: implications from the Japan Lipid Intervention Trial (J-LIT).
Hypertens Res, 30: 119-23, 2007.
           
16. Harauma A, Murayama T, Ikeyama K, Sano H, Arai H, Takano R, Kita T, Hara S, Kamei K, Yokode M.
Mulberry leaf powder prevents atherosclerosis in apolipoprotein E-deficient mice.
Biochem Biophys Res Commun, 358: 751-6, 2007.
           
17. Sumi E, Iehara N, Akiyama H, Matsubara T, Mima A, Kanamori H, Fukatsu A, Salant DJ, Kita T, Arai H, Doi T.
SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cells.
Am J Pathol, 170: 1854-64, 2007.
           
18. Hiraoka Y, Ohno M, Yoshida K, Okawa K, Tomimoto H, Kita T, Nishi E.
Enhancement of alpha-secretase cleavage of amyloid precursor protein by a metalloendopeptidase nardilysin.
J Neurochem, 102: 1595-605, 2007.
           
19. Hirai M, Horiguchi M, Ohbayashi T, Kita T, Chien KR, Nakamura T.
Latent TGF-beta-binding protein 2 binds to DANCE/fibulin-5 and regulates elastic fiber assembly.
EMBO J, 26: 3283-95, 2007.
           
20. Shimada K, Kishimoto C, Okabe TA, Hattori M, Murayama T, Yokode M, Kita T.
Exercise training reduces severity of atherosclerosis in apolipoprotein E knockout mice via nitric oxide.
Circ J, 71: 1147-51, 2007.
           
21. Kanamori H, Matsubara T, Mima A, Sumi E, Nagai K, Takahashi T, Abe H, Iehara N, Fukatsu A, Okamoto H, Kita T, Doi T, Arai H.
Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy.
Biochem Biophys Res Commun, 360: 772-7, 2007.
           
22. Tanaka M, Yamamoto H, Kita T, Yokode M.
Early prediction of the need for non-routine discharge planning for the elderly.
Arch Gerontol Geriatr, 47: 1-7, 2008.
           
23. Arai H, Yamamoto A, Matsuzawa Y, Saito Y, Yamada N, Oikawa S, Mabuchi H, Teramoto T, Sasaki J, Nakaya N, Itakura H, Ishikawa Y, Ouchi Y, Horibe H, Egashira T, Hattori H, Kita T.
Polymorphisms of apolipoprotein e and methylenetetrahydrofolate reductase in the Japanese population.
J Atheroscler Thromb, 14: 167-71, 2007.
           
24. Xu Y, Arai H, Murayama T, Kita T, Yokode M.
Hypercholesterolemia contributes to the development of atherosclerosis and vascular remodeling by recruiting bone marrow-derived cells in cuff-induced vascular injury.
Biochem Biophys Res Commun, 363: 782-7, 2007.
           
25. Akao M, Takeda T, Kita T, Kume T, Akaike A.
Serofendic acid, a substance extracted from fetal calf serum, as a novel drug for cardioprotection.
Cardiovasc Drug Rev, 25: 333-41, 2007.
           
26. Matsuzawa Y, Kita T.
A Trilogy of Primary Prevention Statin Trials: The Impact of These Landmark Studies on Clinical Practice Proceedings of the ISA Sankyo Forum,Rome,Italy 19,2006.
Atherosclerosis Supplements Vol.8, Issue 2 2007.
           
27. Abe M, Kimura T, Furukawa Y, Tadamura E, Kita T.
Coronary Buerger's disease with a peripheral arterial aneurysm.
Eur Heart J, 28: 928, 2007.
           
28. Higashi T, Ikeda T, Shirakawa R, Kondo H, Kawato M, Horiguchi M, Okuda T, Okawa K, Fukai S, Nureki O, Kita T, Horiuchi H.
Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets.
J Biol Chem, 283: 8746-55, 2008.
           
29. Takaya T, Kawamura T, Morimoto T, Ono K, Kita T, Shimatsu A, Hasegawa K.
Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes.
J Biol Chem, 283: 9828-35, 2008.
           
30. Aramaki Y, Mitsuoka H, Toyohara M, Jinnai T, Kanatani K, Nakajima K, Mukai E, Yamada Y, Kita T, Inagaki N, Kume N.
Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells.
Atherosclerosis, 198: 272-9, 2008.
           
31. Mima A, Arai H, Matsubara T, Abe H, Nagai K, Tamura Y, Torikoshi K, Araki M, Kanamori H, Takahashi T, Tominaga T, Matsuura M, Iehara N, Fukatsu A, Kita T, Doi T.
Urinary Smad1 is a novel marker to predict later onset of mesangial matrix expansion in diabetic nephropathy.
Diabetes, 57: 1712-22, 2008.
           
32. Morimoto T, Sunagawa Y, Kawamura T, Takaya T, Wada H, Nagasawa A, Komeda M, Fujita M, Shimatsu A, Kita T, Hasegawa K.
The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats.
J Clin Invest, 118: 868-878, 2008.
           
33. Tabuchi A, Taniguchi R, Takahashi K, Kondo H, Kawato M, Morimoto T, Kimura T, Kita T, Horiuchi H.
Action of aspirin on whole blood-aggregation evaluated by the screen filtration pressure method.
Circ J, 72: 420-6, 2008.
           
34. Xu Y, Arai H, Murayama T, Kita T, Yokode M.
Vascular remodeling and mobilization of bone marrow-derived cells in cuff-induced vascular injury in LDL receptor knockout mice.
Chin Med J (Engl), 5; 121: 220-6, 2008.
           
35. Horie T, Ono K, Kinoshita M, Nishi H, Nagao K, Kawamura T, Abe Y, Wada H, Shimatsu A, Kita T, Hasegawa K.
TG-interacting factor is required for the differentiation of preadipocytes.
J Lipid Res, 49: 1224-34, 2008.
           
36. Hiraoka Y, Yoshida K, Ohno M, Matsuoka T, Kita T, Nishi E.
Ectodomain shedding of TNF-alpha is enhanced by nardilysin via activation of ADAM proteases.
Biochem Biophys Res Commun, 370: 154-8, 2008.
           
37. Matsumae H, Yoshida Y, Ono K, Togi K, Inoue K, Furukawa Y, Nakashima Y, Kojima Y, Nobuyoshi M, Kita T, Tanaka M.
CCN1 knockdown suppresses neointimal hyperplasia in a rat artery balloon injury model.
Arterioscler Thromb Vasc Biol,28: 1077-83, 2008.
           
38. Ozasa N, Morimoto T, Furukawa Y, Shizuta S, Nishiyama K, Kita T, Kimura T.
Effects of ICD implantation on quality-adjusted life years in patients with congestive heart failure.
Int J Cardiol, 123: 213-6, 2008.
           
39. Kawato M, Shirakawa R, Kondo H, Higashi T, Ikeda T, Okawa K, Fukai S, Nureki O, Kita T, Horiuchi H.
Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway.
J Biol Chem, 283: 166-74, 2008.
           
40. Horie T, Ono K, Nagao K, Nishi H, Kinoshita M, Kawamura T, Wada H, Shimatsu A, Kita T, Hasegawa K.
Oxidative stress induces GLUT4 translocation by activation of PI3-K/Akt and dual AMPK kinase in cardiac myocytes.
J Cell Physiol, 215: 733-42, 2008.
           
41. Komori H, Arai H, Kashima T, Huby T, Kita T, Ueda Y.
Coexpression of CLA-1 and human PDZK1 in murine liver modulates HDL cholesterol metabolism.
Arterioscler Thromb Vasc Biol. 28: 1298-303, 2008.
           
42. Ohno S, Kubota T, Yoshida H, Tsuji K, Makiyama T, Yamada S, Kuga K, Yamaguchi I, Kita T, Horie M.
A novel mutation associated with Jervell and Lange-Nielsen syndrome in a Japanese family.
Circ J, 72: 687-93, 2008.
           
43. Tanaka K, Ishikawa Y, Yokoyama M, Origasa H, Matsuzaki M, Saito Y, Matsuzawa Y, Sasaki J, Oikawa S, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K; JELIS Investigators, Japan.
Reduction in the recurrence of stroke by eicosapentaenoic acid for hypercholesterolemic patients: subanalysis of the JELIS trial.
Stroke, 39: 2052-8, 2008.
           
44. Ozasa N, Furukawa Y, Morimoto T, Tadamura E, Kita T, Kimura T.
Relation among left ventricular mass, insulin resistance, and hemodynamic parameters in type 2 diabetes.
Hypertens Res, 31: 425-32, 2008.
           
45. Mitsuoka H, Kume N, Hayashida K, Inui-Hayashiada A, Aramaki Y, Toyohara M, Jinnai T, Nishi E, Kita T.
Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1 (sLOX-1).
Atherosclerosis, 2008, inpress.
           
46. Itakura H, Kita T, Mabuchi H, Matsuzaki M, Matsuzawa Y, Nakaya N, Oikawa S, Saito Y, Sasaki J, Shimamoto K; J-LIT Study Group.
Relationship between coronary events and serum cholesterol during 10 years of low-dose simvastatin therapy: long-term efficacy and safety in Japanese patients with hypercholesterolemia in the Japan Lipid Intervention Trial (J-LIT) Extension 10 Study, a prospective large-scale observational cohort study.
Circ J, 72: 1218-24, 2008.
           
47. Saito Y, Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K; JELIS Investigators, Japan.
Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS).
Atherosclerosis, 200:135-40, 2008.
           
48. Wada H, Abe M, Ono K, Morimoto T, Kawamura T, Takaya T, Satoh N, Fujita M, Kita T, Shimatsu A, Hasegawa K.
Statins activate GATA-6 and induce differentiated vascular smooth muscle cells.
Biochem Biophys Res Commun, 374: 731-6, 2008.
           
49. Morimoto T, Fujita M, Kawamura T, Sunagawa Y, Takaya T, Wada H, Shimatsu A, Kita T, Hasegawa K.
Myocardial regulation of p300 and p53 by doxorubicin involves ubiquitin pathways.
Circ J, 72: 1506-11, 2008.
           
50. Makiyama T, Akao M, Haruna Y, Tsuji K, Doi T, Ohno S, Nishio Y, Kita T, Horie M.
Mutation Analysis of the Glycerol-3 Phosphate Dehydrogenase-1 Like (GPD1L) Gene in Japanese Patients With Brugada Syndrome.
Circ J, 72: 1705-6, 2008.
           
51. Tamura Y, Sugimoto M, Murayama T, Ueda Y, Kanamori H, Ono K, Ariyasu H, Akamizu T, Kita T, Yokode M, Arai H.
Inhibition of CCR2 Ameliorates Insulin Resistance and Hepatic Steatosis in db/db Mice.
Arterioscler Thromb Vasc Biol, 28: 2195-2201, 2008.
           
52. Yamamoto H, Takahashi K, Watanabe H, Yoshikawa Y, Shirakawa R, Higashi T, Kawato M, Ikeda T, Tabuchi A, Morimoto T, Kita T, Horiuchi H.
Evaluation of the Antiplatelet Effects of Cilostazol, a Phosphodiesterase 3 Inhibitor, by VASP Phosphorylation and Platelet Aggregation.
Circ J, 72: 1844-51, 2008.
           
53. Kimura T, Morimoto T, Furukawa Y, Nakagawa Y, Shizuta S, Ehara N, Taniguchi R, Doi T, Nishiyama K, Ozasa N, Saito N, Hoshino K, Mitsuoka H, Abe M, Toma M, Tamura T, Haruna Y, Imai Y, Teramukai S, Fukushima M, Kita T.
Long-term outcomes of coronary-artery bypass graft surgery versus percutaneous coronary intervention for multivessel coronary artery disease in the bare-metal stent era.
Circulation, 118: S199-209, 2008.
           
54. Makiyama T, Akao M, Shizuta S, Doi T, Nishiyama K, Oka Y, Ohno S, Nishio Y, Tsuji K, Itoh H, Kimura T, Kita T, Horie M.
A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation.
J Am Coll Cardiol, 52: 1326-34, 2008.
           
55. Wu YW, Tadamura E, Kanao S, Yamamuro M, Okayama S, Ozasa N, Toma M, Kimura T, Kita T, Marui A, Komeda M, Togashi K. Left ventricular functional analysis using 64-slice multidetector row computed tomography: comparison with left ventriculography and cardiovascular magnetic resonance. Cardiology. 109: 135-42, 2008            
56. Brinkley TE, Kume N, Mitsuoka H, Brown MD, Phares DA, Ferrell RE, Kita T, Hagberg JM. Variation in the human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gene is associated with plasma soluble LOX-1 levels. Exp Physiol. 93: 1085-90, 2008            
57. Furukawa Y, Taniguchi R, Ehara N, Ozasa N, Haruna Y, Saito N, Doi T, Hoshino K, Shizuta S, Morimoto T, Imai Y, Teramukai S, Fukushima M, Kita T, Kimura T; CREDO-Kyoto Investigators. Better survival with statin administration after revascularization therapy in Japanese patients with coronary artery disease: perspectives from the CREDO-Kyoto registry. Circ J. 72:1937-45. 2008